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The Society for Mathematical Biology Annual Meeting and Conference, July 25-28, 2012

SMB 2012 Minisymposia

MS24: Cancer Immunology - July 27, 3:40-5:20 p.m.   SESSION I
Organizer: Kathleen Wilkie (Center of Cancer Systems Biology, Tufts Univ. School of Medicine; Boston, MA, USA)
Presenters: Irina Kareva, Doron Levy, Ami Radunskaya, Kathleen Wilkie

Summary. After a century of controversy and debate, the role of the immune system in modulating cancer progression is now a major focus of current cancer research. Immune cells have been implicated in tumor elimination, but also in maintaining tumor dormancy or even in tumor vascularization and metastasis. The seemingly contradictory roles that immune cells play in tumor development provide a fertile area for mathematical analysis, especially considering the modulation of these actions through chemotherapy or immunotherapy. This minisymposium presents several mathematical approaches to model the cancer-immune biological system. Emphasis is placed on relatively simple mathematical models that capture the complexity of, and provide insights into, cancerimmune dynamics.