STEM Campers Run Like Dinosaurs and Design 3D Models

Adventures in STEM campers 3D print flower models

Campers watch a 3D printer bring their flower model design to life.

Middle school girls from across Tennessee enjoyed trying out different models used in math and science at this year’s Adventures in STEM Camp. The campers used computers to design 3D models of flowers for 3D printing, tested a mathematical model for dinosaur locomotion, and played with Netlogo to learn about agent-based modeling of predator-prey interactions. Fifteen middle school girls participated.

In another activity, girls demonstrated population modeling by pretending to be wolves and deer in an exciting game of “Oh Deer!” They graphed their results outside with sidewalk chalk on one of Knoxville’s Greenways. Other highlights included engineering activities to learn about the power grid, a tour of the UT Veterinary Hospital, and interviews with mathematicians, scientists and engineers.

Campers pose with graphs they created of changing deer and wolf populations from the game "Oh Deer!"

Campers pose with graphs they created of changing deer and wolf populations from the game “Oh Deer!”

NIMBioS and CURENT, an NSF-supported engineering center at UT, have co-organized the week-long day camp since 2012. The camp’s goal is to encourage and inspire middle school girls with STEM interests by delving into a variety of fun hands-on activities, making new friends with shared interests, and by learning about career opportunities in the STEM fields.

Thanks to the many NIMBioS staff, graduate students, and other volunteers that help make this camp possible.

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NIMBioS Teaches the Teachers

Tennessee elementary school teachers measure hip height learned how Alexander's Formula is used to model how fast dinosaurs could move based on their stride length, determined from fossilized footprints, and based on their hip height, determined from fossilized bones. The teachers then took on the role of pretending to be bipedal dinosaurs and performed trials by running outside

Tennessee elementary school teachers measure hip height as a part of an exercise learning how to use Alexander’s Formula to model dinosaur speed. The exercise was part of a workshop training math teachers in ways students can connect math and biology in the classroom.

Tennessee math teachers went back to the classroom this month to learn creative and engaging ways to connect mathematics with biology, led by the NIMBioS Education and Outreach team.

NIMBioS Associate Director for Education and Outreach Suzanne Lenhart, Education and Outreach Coordinator Kelly Sturner, and undergraduate intern Virginia Parkman traveled to Jacksboro Middle School in Campbell County, TN, yesterday to lead a one-day workshop for 23 area elementary and middle-school math teachers. The workshop was part of a longer Tennessee Department of Education “Math Counts II” Workshop.

In this lesson, teachers designing animal shelter cage arrangements.

In this lesson, teachers use array-thinking to design the placement of cages in animal shelters.

The NIMBioS team organized and presented interactive applications of math for grades 3-8, covering modeling, measurement and applications of geometry and array-thinking. Grades 3-5 teachers designed how cages might be arranged in different arrays in an animal shelter to minimize the spread of canine distemper virus. Grades 6-8 teachers learned how Alexander’s Formula is used to model how fast dinosaurs could move based on their stride length, determined from fossilized footprints, and based on their hip height, determined from fossilized bones. The teachers then took on the role of pretending to be bipedal dinosaurs and performed trials by running outside and measuring hip heights. They compared their data to what Alexander’s formula would predict.

In early June, Lenhart and Sturner traveled to Campbell County High School in Jacksboro, TN, for two days as a part of a longer workshop for high school math teachers called “Connecting Math and STEM Through Modeling.” Seventeen math teachers from Campbell County and surrounding counties participated in exercises designed to improve teachers’ understanding of math modeling in the real world. Using resources from Moody’s Mega Math Challenge, Lenhart and Sturner presented the steps involved in using real-world data to generate a modeling equation. Teachers worked in groups and then presented their own model solutions and shared how they might do simple modeling cases with their students.

The workshops were supported by two different grants to Lynn Hodge, associate professor of math education at UT-Knoxville, and Gale Stanley, a retired Campbell County science teacher and currently president of the Tennessee Science Teacher’s Association.

 

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SRE Team Publishes in Frontiers in Microbiology

(From left) Winode Handagama, Magaret McDaniel and Nitin Krishna

(From left) Winode Handagama, Magaret McDaniel and Nitin Krishna

Congratulations to the three students who participated in the 2014 Summer Research Experiences project on mathematical modeling of granuloma formation in Johne’s disease. The team, along with its mentors, has published their results in Frontiers in Microbiology.

“Quantifying limits on replication, death, and quiescence of Mycobacterium tuberculosis in mice” investigates the limits of the rates of bacterial replication, death, and quiescence during Mtb infection in mice. The study found no significant correlation between estimated rates of Mtb replication and death, suggesting the decline in the rates was driven by independent mechanisms. The study also found that the data could not be explained by assuming that bacteria do not die, suggesting that some removal of bacteria from lungs of the mice had to occur even though the total bacterial counts in these mice always increased over time. The study also showed that to explain the data the majority of bacterial cells (at least 60%) must be replicating in the chronic phase of infection, further challenging widespread belief of nonreplicating Mtb in latency.

Co-authors are Margaret McDaniel, who at the time of the program was a student in biochemistry, cellular and molecular biology and mathematics at UT-Knoxville; Nitin Krishna, who was a student in mathematics at the University of Chicago; Winode Handagama, who was a student in biochemistry at Maryville College; along with their mentors: Shigetoshi Eda in the Department of Forestry, Wildlife and Fisheries, UT-Knoxville, and Vitaly Ganusov in the Department of Microbiology, UT-Knoxville.

McDaniel is now a graduate student in immunology at the University of Texas Southwestern Medical School. Her research includes how Mtb triggers a prolonged inflammatory signal.

Krishna is now a junior at the University of Chicago. He is currently a participant in Williams College SMALL Mathematics REU program, studying fluid dynamics and partial differential equations.

Handagama recently graduated from Maryville College.

The publication is available online at http://journal.frontiersin.org/article/10.3389/fmicb.2016.00862/full

Eighteen undergraduates and two high school teachers participated in the 2014 Summer Research Experience at NIMBioS, June 9-August 1. During the eight-week program, participants lived on campus at the University of Tennessee, Knoxville, and worked in teams with NIMBioS postdocs and UT faculty to conduct research at the interface of mathematics and biology. The award included a stipend, housing and some funding to support travel.

More information about NIMBioS’ SRE can be found at https://legacy.nimbios.org/sre/. Currently, 16 undergraduates are participating in the program, working in teams on five different research projects.

 

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Working Group Publishes New Habitat Management Guide

The NIMBioS Working Group on Habitat for Migratory Species enjoys a visit to the mountains during its last meeting at NIMBioS in May. (From left) Chris Welsh, Julia Earl, Christine Sample, Sam Nicol, xx , Gary McCracken, Wayne Thogmartin, Richard Erickson, xx. Seated, from left, Ruscena Wiederholt, Paula Federico, xx, Laura Lopez-Hoffman, Darius Semmens.

The NIMBioS Working Group on Habitat for Migratory Species enjoys a visit to the mountains during its last meeting at NIMBioS in May. (From left) NIMBioS Deputy Director and tour guide Chris Welsh, Julia Earl, Christine Sample, Sam Nicol, Brady Mattsson, Gary McCracken, Wayne Thogmartin, Richard Erickson, Tyler Flockhart. (Seated from left) Ruscena Wiederholt, Paula Federico, Jay Diffendorfer, Laura Lopez-Hoffman, Darius Semmens.

A new management guide for selecting habitat- and patch-specific metrics in spatially-structured populations was published yesterday in Ecological Indicators. The paper is a result of efforts by the NIMBioS Working Group on Habitat for Migratory Species.

The paper reviews the many ways to measure the contribution of a habitat to a population. Some populations, like migratory birds, use many different areas during their lifetimes, making managing such populations a challenge. Which areas should be managed? Not all areas are necessarily equal.

The Group asked the question: What is the best way to measure the value of a habitat to a population, given a particular management objective?

The paper reviews techniques to measure contributions from an applied, management point of view and argues that the best metric for a situation depends on the management goal.

The Working Group began meeting in 2014 and has met four times at NIMBioS, concluding its final meeting in May 2016. Co-organizers are Wayne Thogmartin, Jay Diffendorfer, Ruscena Wiederholt, and Brady Mattsson.

The paper can be viewed at this link for up to 50 days: http://authors.elsevier.com/a/1TAOl_,3LxxlYWs

Nicol S et. al. A management-oriented framework for selecting metrics used to assess habitat- and path-specific quality in spatially structured populations. Ecological Indicators 69: 792-802. DOI:10.1016/j.ecolind.2016.05.027

 

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NIMBioS Welcomes New Postdocs

(From left) Sarah Flanagan, Sergei Tarasov, Nourridine Siewe

(From left) Sarah Flanagan, Sergei Tarasov, Nourridine Siewe

Several new postdoctoral fellows will begin their research soon at NIMBioS.

Joining in the summer are Sarah Flanagan, Nourridine Siewe, and Sergei Tarasov. Flanagan (Biology, Texas A&M Univ.) will develop new predictive approaches for next-generation sequencing population genomics studies. Siewe (Mathematics, Howard Univ.) will develop mathematical models of visceral leishmaniasis and malaria co-infection to improve the diagnosis and treatment process. Tarasov (Mathematics and Natural Sciences, Univ. of Oslo) will model and explore the evolution of anatomy ontologies using innovative stochastic processes and two focal groups of insects: dung beetles and wasps.

Lauren Smith, currently a Gaylord Donnelley Postdoctoral Environmental Fellow at Yale Univ., joins NIMBioS as a postdoc in October. Smith proposes research that examines invasive plants in food-webs and the indirect effects on native communities and ecosystems.

Joining in early 2017 are Andrew Rominger and Oyita Udiani. Rominger (Environmental Science, Policy & Management, Univ. of California, Berkeley) will use bio-collections data and hierarchical models to examine large-scale questions in ecology and evolution. Udiani (Applied Mathematics, Arizona State Univ.) will develop a novel game-theoretical approach to learning in models of animal behavior.

NIMBioS postdoc Robin Taylor (Educational Psychology, Educational Research Methods and Analysis, Auburn University, 2012) began her fellowship last month. As a NIMBioS Postdoctoral Fellow in Science Education Research and Evaluation for NIMBioS Evaluation Services, she is helping to development and validate a Quantitative Biology Concept Inventory, which is designed to assess the efficacy of using real-world biology examples to enhance student understanding of quantitative concepts in college-level calculus courses.

For more information about the NIMBioS Postdoctoral Fellowship, visit https://legacy.nimbios.org/postdocs/

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NIMBioS, UT Welcome New Faculty

Dr. Tian Hong

Dr. Tian Hong

Dr. Monica "Mona" Papes

Dr. Monica “Mona” Papes

NIMBioS welcomes two new NIMBioS-affiliated assistant professors to the University of Tennessee, Knoxville, beginning in January 2017.

Tian Hong will join the Department of Biochemistry and Cellular and Molecular Biology as assistant professor of computational biology. Hong’s research focuses on mathematical modeling of cellular heterogeneity and plasticity and its application in understanding immune response, development and cancer progression. Hong is currently a postdoctoral fellow in the Department of Mathematics at the University of California, Irvine.

Monica Papes will join the Department of Ecology and Evolutionary Biology as an assistant professor in spatial biology. Papes’ research focuses on theoretical and applied investigations centered on species’ distributions. She uses ecological niche modeling techniques with GIS and remote sensing tools to study the factors that shape species’ geographic distributions. Papes is currently an assistant professor in the Department of Integrative Biology at Oklahoma State University.

As both Hong’s and Papes’ research intersects the focus of NIMBioS, both will be affiliated with NIMBioS. Faculty members on the NIMBioS leadership team served on the hiring committees.

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NIMBioS Hosts Field Trip for Rural Middle School Students

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Greenback School sixth graders release their “organisms” back into the “habitat” during the capture-recapture simulation.

Nearly 50 sixth graders and their teachers from Greenback School visited NIMBioS last week for an exciting day of STEM and getting a taste of the college experience. The rural school located about 30 miles southeast of NIMBioS.

Beginning with a mock “university class,” students did a fun hands-on activity created by NIMBioS postdoc Elizabeth Hobson. Students simulated the capture-recapture method of sampling organisms in the wild by using tupperware bins, beans and pine bedding. The activity showed the usefulness of math for doing ecological research.

Next, students headed across the street to Hodges Library for a tour and an introduction to the University of Tennessee’s six-story university library and all of its resources. The students returned to NIMBioS for a pizza lunch, since pizza is an important part of the college experience. Lastly, students walked across campus, past the new Student Union, Neyland Stadium, and UT’s Hill to the Min Kao Computer Science and Engineering building, where students toured energy and robotics engineering labs associated with CURENT, the Center for Ultra-Wide-Area Resilient Electric Energy Transmission Networks, an NSF Engineering Research Center at UT.

More photos from this fun day are posted on our Flickr photo album.

Hobson (left) with Greenback School Students

Hobson (left) with Greenback School students

 

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Vazquez to Receive 2016 Blackwell-Tapia Prize

Dr. Mariel Vazquez 2016 Blackwell-Tapia Prize Recipient

Dr. Mariel Vazquez
2016 Blackwell-Tapia Prize Recipient

KNOXVILLE — The National Blackwell-Tapia Committee is pleased to announce that the 2016 Blackwell-Tapia Prize will be awarded to Mariel Vazquez, a professor in the departments of mathematics and of microbiology and molecular genetics at the University of California, Davis.

The prize is awarded every other year in honor of the legacy of David H. Blackwell and Richard A. Tapia, two distinguished mathematical scientists who have been inspirations to more than a generation of African American, Latino/Latina, and Native American students and professionals in the mathematical sciences. The prize recognizes a mathematician who has contributed significantly to research in his or her field of expertise, and who has served as a role model for mathematical scientists and students from under-represented minority groups or has contributed in other significant ways to addressing the problem of the under-representation of minorities in math.

Vazquez is a pioneer in an emerging field called DNA topology, which applies pure math to untangle the biological mysteries of DNA. Application areas of her research include cancer treatment, drug design, understanding genome rearrangements after radiation damage or in cancer, and gaining insight into how genomes package in viruses and within cells and into how viral DNA (e.g., retroviruses, such as HIV) integrates into the host genome. Vazquez was an academic visitor in the biochemistry department at the University of Oxford, England, in 2006 and 2007 and was a visiting scholar at the University of California, Berkeley in 2008. Vazquez was an academic visitor at the Cancer Research Center in Salamanca, Spain, and an academic visitor at the molecular biology department in the Center for Research and Development in Barcelona, Spain. Vazquez’s research has been supported by grants from the National Institutes of Health and by the National Science Foundation (NSF). In 2012, she was one of only 96 scientists to receive a Presidential Early Career Award for Scientists and Engineers from U.S. President Barack Obama. She was also the recipient of a NSF CAREER award in 2011 for her efforts conducting innovative research and finding creative ways to integrate research and education.

Vazquez has worked passionately to increase diversity in the mathematical sciences at all levels. As a professor at UC Davis since 2014, Vazquez mentors graduate students, has developed an interdisciplinary course in “Analyzing DNA Structure with Mathematical and Computational Methods,” and has served as co-PI on a grant from the National Security Agency to increase the mathematics and statistics components of the 2015-2016 annual conferences of the Society for Advancement of Chicanos/Hispanics and Native Americans in Science. She has also volunteered for other public outreach, including lecturing for the UC Davis Math Circle for middle and high school students. Before joining UC Davis, Vazquez was on the faculty at San Francisco State University where she mentored undergraduates and graduate students and co-founded the elementary school level component of the San Francisco Math Circles.

The prize will be presented at the Ninth Blackwell-Tapia Conference and Awards Ceremony on Oct. 28-29, 2016, at the University of Tennessee, Knoxville. The conference is co-hosted by the National Institute for Mathematical and Biological Synthesis (NIMBioS) and the Statistical and Applied Mathematical Sciences Institute (SAMSI). The conference includes scientific talks, poster presentations, panel discussions and ample opportunities for discussion and interaction. Participants will come from all career stages and will represent institutions of all sizes across the country, including Puerto Rico.

The idea for a conference honoring Blackwell and Tapia came from Carlos Castillo-Chavez, who was a member of the Mathematical Sciences Research Institute’s (MSRI) Human Resources Advisory Committee and a professor of mathematics at Cornell University at the time. Chavez, now a professor at Arizona State University, secured funding from Cornell for the first Blackwell-Tapia Conference in 2000. The award was established two years later under the leadership of Castillo-Chavez and MSRI Director David Eisenbud. Since 2002, the NSF Mathematical Sciences Institutes have served as conference sponsors and hosts. For the 2016 conference, NIMBioS received a grant from the Alfred P. Sloan Foundation to help support the event. Subsequent conferences were held at MSRI (2002), the Institute for Pure & Applied Mathematics (2004 and 2014), the Institute for Mathematics and its Applications (2006), SAMSI (2008), the Mathematical Biosciences Institute (2010), and the Institute for Computational and Experimental Research in Mathematics (2012).

The Blackwell-Tapia Prize was offered for the first time in 2002. Recipients exemplify the high standards of research and service to under-represented minority communities recognized by this award. Past prize recipients include Arlie Petters, Benjamin Powell Professor of Mathematics, Physics, and Business Administration at Duke University (2002); Rodrigo Bañuelos, Professor of Mathematics at Purdue University (2004); William Massey, Edwin S. Wiley Professor of Operations Research and Financial Engineering at Princeton University (2006); Juan Meza, Dean of the School of Natural Sciences at the University of California at Merced (2008); Trachette Jackson, Professor of Mathematics and head of the Jackson Cancer Modeling Group at the University of Michigan (2010); Ricardo Cortez, Pendergraft William Larkin Duren Professor of Mathematics at Tulane University (2012) and Jacqueline Hughes-Oliver, Professor of Statistics, North Carolina State University (2014).

The National Blackwell-Tapia Committee selected the prize recipient. Committee co-chairs are the 2012 and 2014 prize recipients Cortez and Hughes-Oliver. The other committee members are Castillo-Chavez and Eisenbud, as well as Lloyd Douglas, University of North Carolina; Deanna Haunsperger, Carleton College; Suzanne Lenhart, NIMBioS and the University of Tennessee, Knoxville; Bob Megginson, University of Michigan; Kelly Sturner, NIMBioS; and Sherry Woodley, Arizona State University.

As recipient of the 2016 prize, Vazquez now joins the selection committee for the next Blackwell-Tapia prize.

 

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Lenhart Receives Cox Professorship

Suzanne Lenhart Associate Director for Education and Outreach

Suzanne Lenhart
Associate Director for Education and Outreach

Congratulations to NIMBioS Associate Director for Education and Outreach Suzanne Lenhart who has been named a James R. Cox Professor at the University of Tennessee, Knoxville.

A professor of mathematics, Lenhart has been affiliated with NIMBioS since its founding in 2008.

The three-year Cox award will provide Lenhart with a stipend of $25,500 to support her research. Lenhart is an applied mathematician with research publications spanning several areas of biology including HIV, TB, bioreactors, bioeconomics, cardiac function, population dynamics, disease modeling, and resource management. Cox recipients are chosen by a committee for their excellence in teaching, scholarship, and service.

Lenhart follows in the footsteps of other NIMBioS leaders who have earned the honor, NIMBioS Director Emeritus Louis Gross and NIMBioS Associate Director for Postdoctoral Activities Paul Armsworth.

Visit http://tntoday.utk.edu/2016/04/04/ut-honors-mathematician-suzanne-lenhart-cox-professorship/ for the UT press release.

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Announcing the New Roster of Participants for the 2016 Summer Research Experience at NIMBioS

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Two students work on developing mathematical models for their project during last year’s SRE at NIMBioS. (Photo Credit: News Sentinel)

NIMBioS is pleased to announce the 16 undergraduates selected for its highly competitive 2016 Summer Research Experience (SRE) program. Participants were selected from a pool of more than 100 applicants. The program runs for eight weeks, from June 6-July 29. Participants will come to NIMBioS on the University of Tennessee, Knoxville, campus to work in teams with NIMBioS postdocs and UT faculty on research at the interface of mathematics and biology.

2016 SRE participants and their assigned team projects are as follows:

Joshua Darville (Fisk Univ.); Elman Gonzales (East Tennessee State Univ.); and Jan Siess (Rutgers Univ.) will team up on a project to investigate a molecular process called allostery, integral in many biological functions, such as oxygen binding, enzyme regulation, and immune response.

Alana Cooper (Univ. of Tennessee, Knoxville); Emily Horton (Lynchburg College); and Kelly Reagan (Elon Univ.) will work on a project using dynamic modeling to better understand how human emotions unfold over time.

Samuel Iselin (Valparaiso Univ.); Howsikan Kugathasan (Fisk Univ.); and Jacob Miller (Univ. of Kentucky) will work on a project to develop computer games for teaching biology.

Jeff DeSalu (The Ohio State Univ.); Morganne Igoe (Univ. of the Minnesota-Twin Cities); Joey Moran (Unity College); and Theresa Sheets (Univ. of Maryland-Baltimore County) will team up on a project to investigate the effects of different landscapes and resources on hantavirus spread in mice populations.

Alanna Gary (Univ. of Chicago); Vera Liu (Rice Univ.); and Penny Wu (Houghton College) will work on a project using statistical filters to follow fast organelle movements in plant cells

 

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