Quantitative Bioscience at the University of Tennessee

Quantitative Cell Biology

The cell is the basic building block of all life, but while most of the molecular components of the cell have been identified, the emergence of cell structure and behavior from molecular interactions remains a fundamentally mysterious process, as the internal workings of the cell itself take place at a mesoscale level of organization that is not accessible to direct observation. In quantitative cell biology, computer simulations, mathematical models, and quantitative measurement approaches inspired by physics are brought to bear on the question of how cells are put together and function. Quantitative cell biology uses computational and mathematical tools to describe and understand the behavior of a cell. Research also includes quantitative microscopy data acquisition and analysis from experiments. Accurate measurements are used to test predefined hypotheses in order to compare experimental data with predictions generated by theoretical models.

Researcher		Department	Research Interests
	Steve Abel Email	Chemical and Biomolecular Engineering	Computational cell biology and immunology, theory and simulation of soft biological materials, membrane and polymer biophysics, systems biology
	Vasilios Alexiades Email	Mathematics	Math biology (chemotaxis, action potentials, phototransduction), phase change processes (laser ablation, solidification), CFD, parallel computing
	Maitreyi Das Email	Biochemistry and Cellular & Molecular Biology	Study and experimental quantification of cell shape and polarity control
	Judy Day Email	Mathematics; Electrical Engineering & Computer Science	Mathematical modeling and control, dynamical systems, model predictive control, acute inflammation/immunology
	Shigetoshi Eda Email	Forestry, Wildlife and Fisheries; Associate Director, Center for Wildlife Health	Mathematical modeling of Johne's disease epidemiology and immunology, development of an onsite diagnostic system for diseases and physiological conditions
	Vitaly Ganusov Email	Microbiology; Mathematics	Mathematical modeling of CD8 T cell responses to acute and chronic infections
	Hong Guo Email	Biochemistry & Cellular and Molecular Biology	Computational molecular and structural biology
	Tian Hong Email	Biochemistry and Cellular & Molecular Biology	Computational systems biology
	Suzanne Lenhart Email	Mathematics	Optimal control, population and environmental models, natural resource modeling, disease models
	Vasileios Maroulas Email	Mathematics	Topological data analysis, applications of statistical learning methods to neuroscience and biology
	Rachel Patton McCord Email	Biochemistry & Cellular and Molecular Biology	3D genome structure and the biophysics of cell migration
	Andreas Nebenführ Email	Biochemistry & Cellular and Molecular Biology	Cell biology of organelle movement in Arabidopsis
	Steven Wise Email	Mathematics	Mathematical biology, computational materials science, computational and applied math
	Xiaopeng Zhao Email	Mechanical, Aerospace, and Biomedical Engineering	Biommedical signal processing, medical informatics, dynamics and control, computational biology

NIMBioS
1122 Volunteer Blvd., Suite 106
University of Tennessee
Knoxville, TN 37996-3410
PH: (865) 974-9334
FAX: (865) 974-9461
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From 2008 until early 2021, NIMBioS was supported by the National Science Foundation through NSF Award #DBI-1300426, with additional support from The University of Tennessee, Knoxville. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.