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Products of the NIMBioS Working Group:

Within-host modeling of MAP infections


The results of the working group were highlighted in a special issue of the prestigious journal Veterinary Research, which you can read here.

Publications

Eisenberg S, Rutten V, Koets AP. 2015. ​Dam Mycobacterium avium subspecies paratuberculosis (MAP) infection status does not predetermine calves for future shedding when raised in a contaminated environment: a cohort study. Special Issue of Veterinary Research, 46:70. [Online]

Ganusov V, Klinkenberg D, Bakker D, Koets A. 2015. Evaluating contribution of the cellular and humoral immune responses to the control of shedding of Mycobacterium avium spp. paratuberculosis in cattle. Special Issue of Veterinary Research, 46:62. [Online]

Grohn Y, Koets A (eds.). 2015. Modeling Johne's disease: From the inside out. Special Issue of Veterinary Research. [Online]

Klinkenberg D, Koets A. 2015. The long subclinical phase of Mycobacterium avium ssp. paratuberculosis infections explained without adaptive immunity. Special Issue of Veterinary Research, 46:63. [Online]

Koets A, Eda S, Sreevatsan S. 2015. The within host dynamics of Mycobacterium avium ssp. paratuberculosis infection in cattle: where time and place matter. Special Issue of Veterinary Research, 46:61. [Online]

Koets AP, Grohn YT. 2015. Within- and between-host mathematical modeling of Mycobacterium avium subspecies paratuberculosis (MAP) infections as a tool to study the dynamics of host-pathogen interactions in bovine paratuberculosis. Special Issue of Veterinary Research, 46:60. [Online]

Louzoun Y, Mitchell R, Behar H, Schukken Y. 2015. Two state model for a constant disease hazard in paratuberculosis (and other bovine diseases). Special Issue of Veterinary Research, 46:67. [Online]

Martcheva et al. 2015. An immuno-epidemiological model for Johne’s disease in cattle. Special Issue of Veterinary Research, 46:69. [Online]

Mitchell R, Schukken Y, Koets A, Weber M, Bakker D, Stabel J, Whitlock R, Louzoun Y. 2015. Differences in intermittent and continuous fecal shedding patterns between natural and experimental Mycobacterium avium subspecies paratuberculosis infections in cattle. Special Issue of Veterinary Research, 46:66. [Online]

Robins et al. 2015. Agent-based model for Johne’s disease dynamics in a dairy herd. Special Issue of Veterinary Research, 46:68. [Online]

Schukken YH, Whitlock RH, Wolfgang D, Gorhn Y, Beaver A, VanKessel J, Zurakowski M, Mitchell R. 2015. Longitudinal data collection of Mycobacterium avium subspecies Paratuberculosis infections in dairy herds: the value of precise field data. Special Issue of Veterinary Research, 46:65. [Online]

Magombedze G, Eda S, Ganusov VV. 2014. Competition for antigen between Th1 and Th2 responses determines the timing of the immune response switch during Mycobacterium avium subspecies paratuberculosis infection in ruminants. PLoS Computational Biology, 10(1): e1003414. [Online]

Momotani E. 2012. Epidemiological situation and control strategies for paratuberculosis in Japan. The Japanese Journal of Veterinary Research, 60: S19-29. [Online]

Momotani E, Romona NM, Yoshihara K, Momotani Y, Hori M, Ozaki H, Eda S, Ikegami M. 2012. Molecular pathogenesis of bovine paratuberculosis and human inflammatory bowel diseases. Veterinary Immunology and Immunopathology, 148(1-2): 55-68. [Online]

Presentations

Koets AP. June 2015. Keynote lecture: Pathogenomics and MAP biology in Parma, Italy. 12th International Colloquium on Paratuberculosis (ICP).

Koets AP. September 2015. Invited lecture: Vaccination and memory. 5th European Veterinary Immunology Workgroup, Vienna, Austria.

Lenhart S. 2 March 2015. Modeling Johne's Disease in dairy cattle. Colloquium Talk, Univ. of California, Irvine, CA.

Lenhart S. 13 February 2015. Modeling Johne's Disease in dairy cattle. Colloquium Talk, Univ. of Texas, El Paso, TX.

Lenhart S. 27 February 2015. Modeling Johne's Disease in dairy cattle. Colloquium Talk, Arizona State Univ.

Lenhart S. 20 December 2014. Modeling Johne's Disease in dairy cattle. Plenary Talk, Workshop on Mathematical Biology and Nonlinear Analysis, Univ. of Miami.

Lenhart S. 26 November 2014. Modeling Johne's Disease in dairy cattle. Plenary Talk, Southern Africa Mathematical Sciences Association Meeting, Victoria Falls, Zimbabwe.

Lenhart S. 24 October 2014. Modeling Johne's Disease in dairy cattle. Plenary Talk, Mississippi State Conference on Differential Equations and Computational Simulations, Mississippi State Univ.

Momotani E. 5-9 February 2012. Etiological relationship of Mycobacterium avium subsp. paratuberculosis and human Crohn's disease: Histological, molecular comparison and new evidence of the pathogenesis. Sydney, Australia.

Momotani E. 3 February 2012. Epidemic situation and control of paratuberculosis in Japan. International Symposium on Worldwide Infectious Diseases of Farm Animal in Production Medicine: Prospective and Perspective.


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From 2008 until early 2021, NIMBioS was supported by the National Science Foundation through NSF Award #DBI-1300426, with additional support from The University of Tennessee, Knoxville. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
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